OI
5.0评论日期：Jul 14, 2024
Amazing to-the-point course content, great citations to key articles and questions which are very helpful for permenance. I'm pleased as a medical doctor in drug research. Thanks for this course!
This course begins with a review of routes of administration, ADME (absorption, distribution, metabolism, & excretion), and the use of in vivo drug concentration-time data to determine key pharmacokinetic parameters, like volume of distribution, half-life and clearance. The course then emphasizes in vitro assays that allow rapid prediction of ADME and PK properties for evaluation of new compounds. The later stages of the course focus on how drug discovery teams study this PK/PD relationship, as well as dose size and frequency predictions which ultimately assist in selection of a compound for advancement into the clinic.