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学生对 Technical University of Denmark (DTU) 提供的 Whole genome sequencing of bacterial genomes - tools and applications 的评价和反馈

4.6
1,603 个评分

课程概述

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

热门审阅

SP

Sep 30, 2018

This course helped me a lot in determining bacterial typing. Just one question, in some quizzes I got some answers wrong so is there any way of knowing the right answer.

AR

May 18, 2023

Excellent course for students who don't know much about sequencing and its analysis. It's very easy and very understandable for students new to bioinformatics.

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226 - Whole genome sequencing of bacterial genomes - tools and applications 的 250 个评论(共 419 个)

创建者 Unipath B

Dec 15, 2024

Found really helpful & interesting as well

创建者 Laura M

Sep 8, 2022

Very good for starters in bioinformatics!

创建者 Shimul D

May 30, 2020

That was really awesome.Thanks to everyone

创建者 Ahmed E A e

Oct 30, 2018

It isa fantastic course to spend your time

创建者 Kris A S

Dec 7, 2017

Genuinly seems fun.

Keep it up Team at TUD

创建者 Valourstar M

Nov 15, 2017

developing skills in sequencing techniques

创建者 Sonia R Q Q

Sep 16, 2019

a complete an interesting course, thanks!

创建者 Md. A A 1

Jul 25, 2020

Its an awesome and very helpful course

创建者 Shakil A S

Aug 31, 2020

Too much tough but still too amazing!

创建者 Sharma

Nov 25, 2019

Great course. Excellent for research.

创建者 Tavonga D Z

Jul 3, 2022

Great hands-on course. I enjoyed it.

创建者 Dordia R

Jun 26, 2020

practical and clear. Really helpful!

创建者 Deepak S

Apr 1, 2020

Excellent course, great instructors.

创建者 Shahrzad H A

Oct 16, 2023

Great course and great instructors!

创建者 Noor U

Aug 7, 2023

Thank You so much for your efforts.

创建者 huma a

Jul 2, 2022

I have learnt alot from this course

创建者 Eunice O

Sep 26, 2020

such an excellent practical course.

创建者 PADHYA T

Apr 11, 2025

Good Informative and useful course

创建者 Kannan M

Oct 3, 2024

Very Useful, easy to understanding

创建者 Prince M

Oct 29, 2021

AMAZING COURSE THANK YOU VERY MUCH

创建者 Tahir H

Dec 23, 2019

a good experience to get knowledge

创建者 Jenny S

Jun 11, 2020

really helpful and awesome course

创建者 Manaswini K

Jun 9, 2020

very useful ,thank you so much !!

创建者 Rafael P

Jun 3, 2018

Great Course!, congratulations!

创建者 Ibrahim H

Nov 9, 2019

This lecuers exterimly useful.