Investigate the fundamental molecular and cellular mechanisms that govern life processes and human health. Build comprehensive understanding of how biological systems function at the molecular level to support clinical decision-making in nursing practice. Connect molecular principles to patient care scenarios through exploration of metabolism, genetics, and cellular communication pathways essential for understanding pharmacology and pathophysiology.

您将学到什么
Analyze protein structure-function relationships, enzyme mechanisms, and their roles in cellular processes and drug interactions
Evaluate cellular membrane structure, transport mechanisms, and organelle functions that maintain cellular homeostasis
Explain energy metabolism pathways including glycolysis, Krebs cycle, and electron transport chain
Apply knowledge of cell cycle regulation, DNA replication, transcription, and translation to understand genetic disorders and therapeutic targets
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该课程共有4个模块
Biochemistry is the study of biomolecules within living organisms. These compounds are found in every structure and process of every living species and appear to be key in the initiation and maintenance of life as we know it. In this course, the student will be introduced to the basic principles of biochemistry, including the most important concepts regarding carbohydrates, lipids, proteins, and nucleic acids. The levels of protein structures, gene expression, and basic metabolic functions will be covered as well. For optimal comprehension, the student will be required to be familiar with the basic notions of molecular and cellular biology.
涵盖的内容
72个视频12篇阅读材料73个作业
72个视频• 总计300分钟
- Overview• 4分钟
- History• 6分钟
- Structure• 7分钟
- R-group Categories• 2分钟
- Hydrophobic R-groups• 6分钟
- Hydrophilic and Ionic R-groups• 5分钟
- Ionization• 7分钟
- Peptide Bonds• 3分钟
- Polypeptides• 4分钟
- Levels of Protein Structure and Primary Structure• 3分钟
- Secondary Structure• 8分钟
- Tertiary Structure• 6分钟
- Quaternary Structure and Summary• 3分钟
- Structure of Proteins• 5分钟
- Globular Structural Proteins• 2分钟
- Communication and Signaling• 8分钟
- Involved Proteins• 5分钟
- Antibodies• 3分钟
- Gene Expression• 4分钟
- Catalysis• 5分钟
- Protein Transport• 2分钟
- Oxygen Transport• 5分钟
- Sodium-potassium ATPase• 4分钟
- Saccharides• 2分钟
- Common Sugars: Nomenclature & Structure• 7分钟
- Cyclization & Cyclic Forms• 7分钟
- Modified Sugars• 2分钟
- Glycosides and Disaccharides• 4分钟
- Polysaccharides• 4分钟
- Lipid Links• 3分钟
- Glycosaminoglycans• 4分钟
- Protein Links• 5分钟
- Peptidoglycans• 3分钟
- Proteoglycans• 3分钟
- Overview and Introduction on Fatty Acids• 3分钟
- Fatty Acids• 4分钟
- Glycerolipids and Glycerophospholipids• 5分钟
- Sphingolipids• 3分钟
- Polyketides• 1分钟
- Overview, Isoprenoids and Sterols• 4分钟
- Steroid Hormones• 3分钟
- Other Lipids and Their Function• 6分钟
- Fat Soluble Vitamins• 5分钟
- Structure of Membranes• 1分钟
- Lipid Bilayer• 2分钟
- Bilayer Composition• 6分钟
- Membrane Fluidity• 2分钟
- Diffusion• 5分钟
- Active Transport: Sodium-potassium Atpase• 5分钟
- Active Transport: Sodium-calcium Exchanger• 3分钟
- Transporter and Transport Proteins Types• 3分钟
- Ion Channel• 6分钟
- Ion Channel Blocker and Opener• 5分钟
- Nucleotides• 4分钟
- Structure and Topology of DNA• 5分钟
- DNA Replication• 1分钟
- Transcription• 6分钟
- Messenger RNAs• 4分钟
- Structure of TRNA and RRNA• 6分钟
- Genetic Code• 5分钟
- TRNA Charging and Ribosomes• 2分钟
- Translation• 4分钟
- Energy Considerations• 6分钟
- Metabolism• 7分钟
- Oxidation and Reduction• 3分钟
- Electron Carriers• 3分钟
- Catabolism and Anabolism• 4分钟
- Metabolic Pathways• 3分钟
- Regulation of Enzymatic Activity• 5分钟
- Allosterism• 3分钟
- Covalent Modification• 3分钟
- Gene Expression• 3分钟
12篇阅读材料• 总计360分钟
- Introduction to Biochemistry• 30分钟
- Amino Acids• 30分钟
- Peptides• 30分钟
- Protein Movement and Cell Signaling• 30分钟
- Protein Functions• 30分钟
- Simple Carbohydrates• 30分钟
- Complex Carbohydrates• 30分钟
- Lipids• 30分钟
- Biological Membranes• 30分钟
- DNA, RNA and the Genetic Code• 30分钟
- Oxidation and Reduction in Metabolism• 30分钟
- Metabolism and Regulation• 30分钟
73个作业• 总计390分钟
- Overview: Quiz• 5分钟
- History: Quiz• 5分钟
- Structure: Quiz• 5分钟
- R-group Categories: Quiz• 5分钟
- Hydrophobic R-groups: Quiz• 5分钟
- Hydrophilic and Ionic R-groups: Quiz• 5分钟
- Ionization: Quiz• 5分钟
- Peptide Bonds: Quiz• 5分钟
- Polypeptides: Quiz• 5分钟
- Levels of Protein Structure and Primary Structure: Quiz• 5分钟
- Secondary Structure: Quiz• 5分钟
- Tertiary Structure: Quiz• 5分钟
- Quaternary Structure and Summary: Quiz• 5分钟
- Structure of Proteins: Quiz• 5分钟
- Globular Structural Proteins: Quiz• 5分钟
- Communication and Signaling: Quiz• 5分钟
- Involved Proteins: Quiz• 5分钟
- Antibodies: Quiz• 5分钟
- Gene Expression: Quiz• 5分钟
- Catalysis: Quiz• 5分钟
- Protein Transport: Quiz• 5分钟
- Oxygen Transport: Quiz• 5分钟
- Sodium-potassium ATPase: Quiz• 5分钟
- Saccharides: Quiz• 5分钟
- Common Sugars: Nomenclature & Structure: Quiz• 5分钟
- Cyclization & Cyclic Forms: Quiz• 5分钟
- Modified Sugars: Quiz• 5分钟
- Glycosides and Disaccharides: Quiz• 5分钟
- Polysaccharides: Quiz• 5分钟
- Lipid Links: Quiz• 5分钟
- Glycosaminoglycans: Quiz• 5分钟
- Protein Links: Quiz• 5分钟
- Peptidoglycans: Quiz• 5分钟
- Proteoglycans: Quiz• 5分钟
- Overview and Introduction on Fatty Acids: Quiz• 5分钟
- Fatty Acids: Quiz• 5分钟
- Glycerolipids and Glycerophospholipids: Quiz• 5分钟
- Sphingolipids: Quiz• 5分钟
- Polyketides: Quiz• 5分钟
- Overview, Isoprenoids and Sterols: Quiz• 5分钟
- Steroid Hormones: Quiz• 5分钟
- Other Lipids and Their Function: Quiz• 5分钟
- Fat Soluble Vitamins: Quiz• 5分钟
- Structure of Membranes: Quiz• 5分钟
- Lipid Bilayer: Quiz• 5分钟
- Bilayer Composition: Quiz• 5分钟
- Membrane Fluidity: Quiz• 5分钟
- Diffusion: Quiz• 5分钟
- Active Transport: Sodium-potassium Atpase: Quiz• 5分钟
- Active Transport: Sodium-calcium Exchanger: Quiz• 5分钟
- Transporter and Transport Proteins Types: Quiz• 5分钟
- Ion Channel: Quiz• 5分钟
- Ion Channel Blocker and Opener: Quiz• 5分钟
- Nucleotides: Quiz• 5分钟
- Structure and Topology of DNA: Quiz• 5分钟
- DNA Replication: Quiz• 5分钟
- Transcription: Quiz• 5分钟
- Messenger RNAs: Quiz• 5分钟
- Structure of TRNA and RRNA: Quiz• 5分钟
- Genetic Code: Quiz• 5分钟
- TRNA Charging and Ribosomes: Quiz• 5分钟
- Translation: Quiz• 5分钟
- Energy Considerations: Quiz• 5分钟
- Metabolism: Quiz• 5分钟
- Oxidation and Reduction: Quiz• 5分钟
- Electron Carriers: Quiz• 5分钟
- Catabolism and Anabolism: Quiz• 5分钟
- Metabolic Pathways: Quiz• 5分钟
- Regulation of Enzymatic Activity: Quiz• 5分钟
- Allosterism: Quiz• 5分钟
- Covalent Modification: Quiz• 5分钟
- Gene Expression: Quiz• 5分钟
- Biochemistry: Basics – Final Quiz• 30分钟
Cellular functioning, movement, and communication rely on the cytoskeleton, a large internal network of protein filaments embedded in the cytosol and anchored to the cell membrane. In this course, the student will be introduced to the composition and function of the cytoskeleton, mechanisms of molecular transport, modes of cell communication, and second messengers. For optimal comprehension, the student will be required to be familiar with the basic concepts of college-grade biology and chemistry.
涵盖的内容
29个视频7篇阅读材料30个作业
29个视频• 总计128分钟
- Introduction to the Cellular Structure• 4分钟
- Nucleus and Ribosomes• 4分钟
- Endomembrane System• 2分钟
- Endoplasmic Reticulum and Golgi Apparatus• 3分钟
- Lysosomes• 3分钟
- Mitochondria and Origins of Eukaryotic Cells• 4分钟
- Introduction to Membranes• 1分钟
- Fluid Mosaic Model• 5分钟
- Role of Cell Membrane Proteins• 4分钟
- How Proteins Anchor Themselves in the Membrane• 3分钟
- Passive Transport• 7分钟
- Osmosis and Tonicity• 8分钟
- Active Transport• 8分钟
- Bulk Transport• 5分钟
- Cytoskeleton• 5分钟
- Transport and Network of Proteins• 3分钟
- Extracellular Structures and Cell Movement• 3分钟
- Cell Identity• 3分钟
- Three Types of Cell Junctions• 5分钟
- Introduction• 3分钟
- Modes of Cell Communication: Overview• 6分钟
- Phosphorylation• 3分钟
- Cell Surface Receptors• 5分钟
- Intracellular Receptors• 5分钟
- Overview• 2分钟
- Second Messenger Systems: Definition• 4分钟
- Receptor Tyrosine Kinase Pathways• 13分钟
- G-protein Coupled Receptors• 8分钟
- Recap• 3分钟
7篇阅读材料• 总计210分钟
- The Blueprint of the Cell• 30分钟
- The Dynamic Cell Membrane• 30分钟
- Transport Across Cell Membranes• 30分钟
- Cellular Scaffolding and Movement• 30分钟
- Establishing Identity and Connections• 30分钟
- Introduction to Cell Communication• 30分钟
- Second Messengers and Signaling Pathways• 30分钟
30个作业• 总计175分钟
- Introduction to the Cellular Structure: Quiz• 5分钟
- Nucleus and Ribosomes: Quiz• 5分钟
- Endomembrane System: Quiz• 5分钟
- Endoplasmic Reticulum and Golgi Apparatus: Quiz• 5分钟
- Lysosomes: Quiz• 5分钟
- Mitochondria and Origins of Eukaryotic Cells: Quiz• 5分钟
- Introduction to Membranes: Quiz• 5分钟
- Fluid Mosaic Model: Quiz• 5分钟
- Role of Cell Membrane Proteins: Quiz• 5分钟
- How Proteins Anchor Themselves in the Membrane: Quiz• 5分钟
- Passive Transport: Quiz• 5分钟
- Osmosis and Tonicity: Quiz• 5分钟
- Active Transport: Quiz• 5分钟
- Bulk Transport: Quiz• 5分钟
- Cytoskeleton: Quiz• 5分钟
- Transport and Network of Proteins: Quiz• 5分钟
- Extracellular Structures and Cell Movement: Quiz• 5分钟
- Cell Identity: Quiz• 5分钟
- Three Types of Cell Junctions: Quiz• 5分钟
- Introduction: Quiz• 5分钟
- Modes of Cell Communication: Overview: Quiz• 5分钟
- Phosphorylation: Quiz• 5分钟
- Cell Surface Receptors: Quiz• 5分钟
- Intracellular Receptors: Quiz• 5分钟
- Overview: Quiz• 5分钟
- Second Messenger Systems: Definition: Quiz• 5分钟
- Receptor Tyrosine Kinase Pathways: Quiz• 5分钟
- G-protein Coupled Receptors: Quiz• 5分钟
- Recap: Quiz• 5分钟
- Cellular Structure – Final Quiz• 30分钟
Cells, as the fundamental unit of living organisms, also have a life cycle. The cell cycle is a series of phases a cell undergoes to reach division into a new generation of cells and perpetuate its genetic material. Each phase encapsulates different processes required to ensure the daughter cells are well equipped to begin their own cycles after division. In this course, the student will be given a walkthrough of the phases of the cell cycle and all the processes that take place during each one, finishing with a discussion of diploid and haploid cell division. For optimal comprehension, the student will be required to be familiar with the basic concepts of college-grade biology and chemistry.
涵盖的内容
22个视频6篇阅读材料23个作业
22个视频• 总计75分钟
- Introduction• 3分钟
- Cell Cycle Controls• 9分钟
- Growth Factors• 3分钟
- P53 Gene• 3分钟
- Mutated Genes• 5分钟
- Two Hit Hypothesis• 3分钟
- Overview• 1分钟
- Language of Chromosomes• 3分钟
- Eukaryotic Chromosomes• 3分钟
- Cell Division• 2分钟
- Interphase and Prophase• 2分钟
- Prometaphase, Metaphase and Anaphase• 4分钟
- Telophase and Cytokinesis• 5分钟
- Introduction and Reduce of Chromosomes• 6分钟
- Homologous Chromosome Pairs• 3分钟
- Human Karyotype• 1分钟
- Meiosis I: Prophase I• 2分钟
- Meiosis I: Metaphase I• 4分钟
- Meiosis I: Anaphase I and Telophase I• 2分钟
- Meiosis II: Phases• 4分钟
- Meiosis in Humans• 3分钟
- Comparing Mitosis and Meiosis – Cell Division• 4分钟
6篇阅读材料• 总计180分钟
- Setting the Stage – Cell Cycle and Its Regulation• 30分钟
- When Control Fails – Cancer-Related Genes• 30分钟
- Mitosis – The Mechanics of Cell Division• 30分钟
- Chromosomes and Reduction Division• 30分钟
- Meiosis – Creating Diversity• 30分钟
- Mitosis vs. Meiosis – Comparing the Strategies• 30分钟
23个作业• 总计140分钟
- Introduction: Quiz• 5分钟
- Cell Cycle Controls: Quiz• 5分钟
- Growth Factors: Quiz• 5分钟
- P53 Gene: Quiz• 5分钟
- Mutated Genes: Quiz• 5分钟
- Two Hit Hypothesis: Quiz• 5分钟
- Overview: Quiz• 5分钟
- Language of Chromosomes: Quiz• 5分钟
- Eukaryotic Chromosomes: Quiz• 5分钟
- Cell Division: Quiz• 5分钟
- Interphase and Prophase: Quiz• 5分钟
- Prometaphase, Metaphase and Anaphase: Quiz• 5分钟
- Telophase and Cytokinesis: Quiz• 5分钟
- Introduction and Reduce of Chromosomes: Quiz• 5分钟
- Homologous Chromosome Pairs: Quiz• 5分钟
- Human Karyotype: Quiz• 5分钟
- Meiosis I: Prophase I: Quiz• 5分钟
- Meiosis I: Metaphase I: Quiz• 5分钟
- Meiosis I: Anaphase I and Telophase I: Quiz• 5分钟
- Meiosis II: Phases: Quiz• 5分钟
- Meiosis in Humans: Quiz• 5分钟
- Comparing Mitosis and Meiosis – Cell Division: Quiz• 5分钟
- Cell Cycle and Cell Division – Final Quiz• 30分钟
All organisms require energy to function. By utilizing energy, living organisms oppose the breakdown of their systems brought about by contact with the external environment. Energy is extracted from biomolecules by cells via catabolic pathways and cellular respiration. In this course, the student will be introduced to the cellular processes of energy synthesis in the form of adenosine triphosphate (ATP). For optimal comprehension, the student will be required to be familiar with the basic concepts of college-grade biology, chemistry, and physics, with an emphasis on the laws of thermodynamics.
涵盖的内容
25个视频8篇阅读材料27个作业
25个视频• 总计84分钟
- Definition of Energy• 3分钟
- Laws of Thermodynamics• 4分钟
- Chemical, Endergonic and Exergonic Reactions• 4分钟
- Activation Energy of Reactions• 2分钟
- Bicarbonate Buffering System• 4分钟
- ATP – Adenosine Triphosphate• 2分钟
- Electrochemical Gradient• 4分钟
- ATP Synthase• 3分钟
- Activation and Inhibition• 3分钟
- Assisting Enzymes• 2分钟
- Biochemical Pathways• 3分钟
- Metabolic Pathways• 4分钟
- Process of Metabolism• 4分钟
- Overview• 7分钟
- A Review of Glycolysis• 2分钟
- Pyruvate Oxidation• 2分钟
- Anaerobic Glycolysis• 4分钟
- Recycling of NADH• 2分钟
- Krebs Cycle• 7分钟
- Electron Transport Chain (ETC)• 2分钟
- Electron Transport Chain (ETC) and Chemiosmosis• 2分钟
- Introduction• 1分钟
- Entry Points into Cellular Respiration• 2分钟
- Catabolism of Fats and Proteins• 4分钟
- Cell Respiration• 6分钟
8篇阅读材料• 总计240分钟
- Nature of Energy and Life• 30分钟
- How Reactions Happen• 30分钟
- ATP – The Energy Currency• 30分钟
- Enzymes – Catalysts of Life• 30分钟
- Metabolic Pathways – The Cell’s Roadmaps• 30分钟
- Glycolysis and Pyruvate Oxidation• 30分钟
- Krebs Cycle and Electron Transport• 30分钟
- Metabolism in Context• 30分钟
27个作业• 总计245分钟
- Definition of Energy: Quiz• 5分钟
- Laws of Thermodynamics: Quiz• 5分钟
- Chemical, Endergonic and Exergonic Reactions: Quiz• 5分钟
- Activation Energy of Reactions: Quiz• 5分钟
- Bicarbonate Buffering System: Quiz• 5分钟
- ATP – Adenosine Triphosphate: Quiz• 5分钟
- Electrochemical Gradient: Quiz• 5分钟
- ATP Synthase: Quiz• 5分钟
- Activation and Inhibition: Quiz• 5分钟
- Assisting Enzymes: Quiz• 5分钟
- Biochemical Pathways: Quiz• 5分钟
- Metabolic Pathways: Quiz• 5分钟
- Process of Metabolism: Quiz• 5分钟
- Overview: Quiz• 5分钟
- A Review of Glycolysis: Quiz• 5分钟
- Pyruvate Oxidation: Quiz• 5分钟
- Anaerobic Glycolysis: Quiz• 5分钟
- Recycling of NADH: Quiz• 5分钟
- Krebs Cycle: Quiz• 5分钟
- Electron Transport Chain (ETC): Quiz• 5分钟
- Electron Transport Chain (ETC) and Chemiosmosis: Quiz• 5分钟
- Introduction: Quiz• 5分钟
- Entry Points into Cellular Respiration: Quiz• 5分钟
- Catabolism of Fats and Proteins: Quiz• 5分钟
- Cell Respiration: Quiz• 5分钟
- Energy, Enzymes and Metabolism – Final Quiz• 30分钟
- Project: "Cellular Process Analysis"• 90分钟
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